Tramadol 50 mg/ml Lavoisier Glass ampoule, injectable solution

THERAPEUTIC INDICATIONS

Management of moderate to severe pain in adults, especially post-surgical pains.

PHARMACEUTICAL FORM

Tramadol is available in glass ampoule with an OPC (one point cut) opening system.

PHARMACO-THERAPEUTIC CLASS

Other opioid (ATC Code: N02AX02)

PHARMACODYNAMICS

Tramadol is a centrally acting synthetic analgesic compound, which effectiveness at therapeutic doses is due to the synergy:

• of an opioid effect due to fixation on μ opioid receptors,
• of a central monoaminergic effect due to inhibition of reuptake of norepinephrine / noradrenaline and serotonin, acting as a control mechanism of the central nociceptive transmission.

Like other products of this class, Tramadol has antitussive properties. At therapeutic doses, the effect of Tramadol on the gastro-intestinal tract is minimal. The respiratory depressant effects of Tramadol are lower than those of morphine. Animal research has demonstrated a low dependence potential compared to morphine, and a minimal tolerance potential.